Modulation of Susceptibility to HIV-1 Infection by the Cytotoxic T Lymphocyte Antigen 4 Costimulatory Molecule

Modulation of Susceptibility to HIV-1 Infection by the Cytotoxic T Lymphocyte Antigen 4 Costimulatory Molecule

CD4 T cells activated in vitro by anti-CD3/28–coated beads are resistant to infection by CC chemokine receptor 5 (CCR5)-dependent HIV-1 isolates. In vivo, antigen-presenting cells (APCs) activate CD4 T cells in part by signaling through the T cell receptor and CD28, yet cells stimulated in this mann...

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Bibliographic Details
Main Authors: Riley, James L., Schlienger, Katia, Blair, Patrick J., Carreno, Beatriz, Craighead, Nancy, Kim, Daniel, Carroll, Richard G., June, Carl H.
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213525/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213525/

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