Costimulatory pathways in transplantation
► Costimulatory pathways have a critical role in the regulation of alloreactivity. ► A complex network of positive and negative pathways regulates T cell responses. ► Blocking costimulation improves allograft survival in rodents and non-human primates. ► The costimulation blocker belatacept is being...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Academic Press
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203219/ |