A Novel, Non-canonical Splice Variant of the Ikaros Gene Is Aberrantly Expressed in B-cell Lymphoproliferative Disorders

A Novel, Non-canonical Splice Variant of the Ikaros Gene Is Aberrantly Expressed in B-cell Lymphoproliferative Disorders

The Ikaros gene encodes a Krüppel-like zinc-finger transcription factor involved in hematopoiesis regulation. Ikaros has been established as one of the most clinically relevant tumor suppressors in several hematological malignancies. In fact, expression of dominant negative Ikaros isoforms is associ...

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Bibliographic Details
Main Authors: Capece, Daria, Zazzeroni, Francesca, Mancarelli, Maria Michela, Verzella, Daniela, Fischietti, Mariafausta, Di Tommaso, Ambra, Maccarone, Rita, Plebani, Sara, Di Ianni, Mauro, Gulino, Alberto, Alesse, Edoardo
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706598/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706598/

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