Deaminase-independent inhibition of HIV-1 reverse transcription by APOBEC3G

Deaminase-independent inhibition of HIV-1 reverse transcription by APOBEC3G

APOBEC3G (A3G), a host protein that inhibits HIV-1 reverse transcription and replication in the absence of Vif, displays cytidine deaminase and single-stranded (ss) nucleic acid binding activities. HIV-1 nucleocapsid protein (NC) also binds nucleic acids and has a unique property, nucleic acid chape...

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Bibliographic Details
Main Authors: Iwatani, Yasumasa, Chan, Denise S.B., Wang, F., Maynard, Kristen Stewart, Sugiura, Wataru, Gronenborn, Angela M., Rouzina, Ioulia, Williams, Mark C., Musier-Forsyth, Karin, Levin, Judith G.
Format: Online
Language:English
Published: Oxford University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175344/

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