Intrinsic immunity against retrotransposons by APOBEC cytidine deaminases
Over 40% of the human genome is recognizable as having been derived from ancient retroelements, transported by an intracellular copy-and-paste process involving an RNA intermediate, with an additional few percent classified as DNA transposable elements. Endogenous retroviruses are long terminal repe...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
Frontiers Media S.A.
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576619/ |