Mutation Processes in 293-Based Clones Overexpressing the DNA Cytosine Deaminase APOBEC3B

Mutation Processes in 293-Based Clones Overexpressing the DNA Cytosine Deaminase APOBEC3B

Molecular, cellular, and clinical studies have combined to demonstrate a contribution from the DNA cytosine deaminase APOBEC3B (A3B) to the overall mutation load in breast, head/neck, lung, bladder, cervical, ovarian, and other cancer types. However, the complete landscape of mutations attributable...

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Bibliographic Details
Main Authors: Akre, Monica K., Starrett, Gabriel J., Quist, Jelmar S., Temiz, Nuri A., Carpenter, Michael A., Tutt, Andrew N. J., Grigoriadis, Anita, Harris, Reuben S.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862684/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862684/

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