pERK-dependent defective TCR-mediated activation of CD4+ T cells in end-stage renal disease patients
Abstract Background Patients with end-stage renal disease (ESRD) have an impaired immune response with a prematurely aged T-cell system. Mitogen-activated protein kinases (MAPKs) including extracellular signal-regulated kinase (ERK) and p38, regulate diverse cellular programs by transferring extrace...
Main Authors: | Ling Huang, Nicolle H. R. Litjens, Nynke M. Kannegieter, Mariska Klepper, Carla C. Baan, Michiel G. H. Betjes |
---|---|
Format: | Article |
Language: | English |
Published: |
BioMed Central
2017-06-01
|
Series: | Immunity & Ageing |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12979-017-0096-1 |
Similar Items
-
2-arachidonyl glycerol modulates astrocytic glutamine synthetase via p38 and ERK1/2 pathways
by: Shenghong Wang, et al.
Published: (2018-08-01) -
Interactions between Sirt1 and MAPKs regulate astrocyte activation induced by brain injury in vitro and in vivo
by: Dan Li, et al.
Published: (2017-03-01) -
Granulin epithelin precursor promotes colorectal carcinogenesis by activating MARK/ERK pathway
by: Yi Pan, et al.
Published: (2018-06-01) -
Serendipitous discovery of light-induced (In Situ) formation of an Azo-bridged dimeric sulfonated naphthol as a potent PTP1B inhibitor
by: Robert D. Bongard, et al.
Published: (2017-05-01) -
Supervillin promotes epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma in hypoxia via activation of the RhoA/ROCK-ERK/p38 pathway
by: Xueran Chen, et al.
Published: (2018-06-01)