Granulin epithelin precursor promotes colorectal carcinogenesis by activating MARK/ERK pathway

Granulin epithelin precursor promotes colorectal carcinogenesis by activating MARK/ERK pathway

Abstract Background Granulin epithelin precursor (GEP) is reported to function as a growth factor stimulating proliferation and migration, and conferring chemoresistance in many cancer types. However, the expression and functional roles of GEP in colorectal cancer (CRC) remain elusive. The aim of th...

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Bibliographic Details
Main Authors: Yi Pan, Siu Tim Cheung, Joanna Hung Man Tong, Ka Yee Tin, Wei Kang, Raymond Wai Ming Lung, Feng Wu, Hui Li, Simon Siu Man Ng, Tony Wing Chung Mak, Ka Fai To, Anthony Wing Hung Chan
Format: Article
Language:English
Published: BioMed Central 2018-06-01
Series:Journal of Translational Medicine
Subjects:
Colorectal cancer
GEP
Oncogene
MAPK/ERK pathway
Online Access:http://link.springer.com/article/10.1186/s12967-018-1530-7

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http://link.springer.com/article/10.1186/s12967-018-1530-7

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