Transgelin-2 is a novel target of KRAS-ERK signaling involved in the development of pancreatic cancer

Abstract Background The KRAS mutation is the driving force of pancreatic ductal adenocarcinoma (PDAC). Downstream effectors of KRAS signal pathways are crucial to the development of PDAC. The purpose of this study was to investigate the relationship between KRAS mutation and transgelin-2. Transgelin...

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Bibliographic Details
Main Authors: Yan Sun, Wenfang Peng, Weiwei He, Man Luo, Guilin Chang, Jiping Shen, Xiaoping Zhao, Yu Hu
Format: Article
Language:English
Published: BioMed Central 2018-07-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
ERK
Online Access:http://link.springer.com/article/10.1186/s13046-018-0818-z