Safety and immunogenicity of multi-antigen AMA1-based vaccines formulated with CoVaccine HT™ and Montanide ISA 51 in rhesus macaques

by Kusi, Kwadwo A, Remarque, Edmond J, Riasat, Vanessa, Walraven, Vanessa, Thomas, Alan W, Faber, Bart W, Kocken, Clemens HM
Published 2011

Immunization with different PfAMA1 alleles in sequence induces clonal imprint humoral responses that are similar to responses induced by the same alleles as a vaccine cocktail in r...

by Kusi, Kwadwo A, Faber, Bart W, van der Eijk, Marjolein, Thomas, Alan W, Kocken, Clemens HM, Remarque, Edmond J
Published 2011

A Malaria Vaccine Based on the Polymorphic Block 2 Region of MSP-1 that Elicits a Broad Serotype-Spanning Immune Response

by Cowan, Graeme J. M., Creasey, Alison M., Dhanasarnsombut, Kelwalin, Thomas, Alan W., Remarque, Edmond J., Cavanagh, David R.
Published 2011

Transfection of the Primate Malaria Parasite Plasmodium knowlesi Using Entirely Heterologous Constructs

by van der Wel, Anna M., Tomás, Ana M., Kocken, Clemens H.M., Malhotra, Pawan, Janse, Chris J., Waters, Andrew P., Thomas, Alan W.
Published 1997

Vaccination with Plasmodium knowlesi AMA1 Formulated in the Novel Adjuvant Co-Vaccine HT™ Protects against Blood-Stage Challenge in Rhesus Macaques

by Mahdi Abdel Hamid, Muzamil, Remarque, Edmond J., van Duivenvoorde, Leonie M., van der Werff, Nicole, Walraven, Vanessa, Faber, Bart W., Kocken, Clemens H. M., Thomas, Alan W.
Published 2011

Humoral Immune Responses to a Single Allele PfAMA1 Vaccine in Healthy Malaria-Naïve Adults

by Remarque, Edmond J., Roestenberg, Meta, Younis, Sumera, Walraven, Vanessa, van der Werff, Nicole, Faber, Bart W., Leroy, Odile, Sauerwein, Robert, Kocken, Clemens H. M., Thomas, Alan W.
Published 2012

Crystal Structure of Plasmodium knowlesi Apical Membrane Antigen 1 and Its Complex with an Invasion-Inhibitory Monoclonal Antibody

by Vulliez-Le Normand, Brigitte, Faber, Bart W., Saul, Frederick A., van der Eijk, Marjolein, Thomas, Alan W., Singh, Balbir, Kocken, Clemens H. M., Bentley, Graham A.
Published 2015

Towards an In Vitro Model of Plasmodium Hypnozoites Suitable for Drug Discovery

by Dembele, Laurent, Gego, Audrey, Zeeman, Anne-Marie, Franetich, Jean-François, Silvie, Olivier, Rametti, Armelle, Le Grand, Roger, Dereuddre-Bosquet, Nathalie, Sauerwein, Robert, van Gemert, Geert-Jan, Vaillant, Jean-Christophe, Thomas, Alan W., Snounou, Georges, Kocken, Clemens H. M., Mazier, Dominique
Published 2011

Proteomic and Genetic Analyses Demonstrate that Plasmodium berghei Blood Stages Export a Large and Diverse Repertoire of Proteins*

by Pasini, Erica M., Braks, Joanna A., Fonager, Jannik, Klop, Onny, Aime, Elena, Spaccapelo, Roberta, Otto, Thomas D., Berriman, Matt, Hiss, Jan A., Thomas, Alan W., Mann, Matthias, Janse, Chris J., Kocken, Clemens H. M., Franke-Fayard, Blandine
Published 2013

Antibody Responses to a Novel Plasmodium falciparum Merozoite Surface Protein Vaccine Correlate with Protection against Experimental Malaria Infection in Aotus Monkeys

by Cavanagh, David R., Kocken, Clemens H. M., White, John H., Cowan, Graeme J. M., Samuel, Kay, Dubbeld, Martin A., der Wel, Annemarie Voorberg-van, Thomas, Alan W., McBride, Jana S., Arnot, David E.
Published 2014

Production, Quality Control, Stability and Pharmacotoxicity of a Malaria Vaccine Comprising Three Highly Similar PfAMA1 Protein Molecules to Overcome Antigenic Variation

by Faber, Bart W., Hellwig, Stephan, Houard, Sophie, Havelange, Nicolas, Drossard, Jürgen, Mertens, Hubert, Croon, Alexander, Kastilan, Robin, Byrne, Richard, van der Werff, Nicole, van der Eijk, Marjolein, Thomas, Alan W., Kocken, Clemens H. M., Remarque, Edmond J.
Published 2016

Genome sequencing of chimpanzee malaria parasites reveals possible pathways of adaptation to human hosts

by Otto, Thomas D., Rayner, Julian C., Böhme, Ulrike, Pain, Arnab, Spottiswoode, Natasha, Sanders, Mandy, Quail, Michael, Ollomo, Benjamin, Renaud, François, Thomas, Alan W., Prugnolle, Franck, Conway, David J., Newbold, Chris, Berriman, Matthew
Published 2014

Reduced CD36-dependent tissue sequestration of Plasmodium-infected erythrocytes is detrimental to malaria parasite growth in vivo

by Fonager, Jannik, Pasini, Erica M., Braks, Joanna A.M., Klop, Onny, Ramesar, Jai, Remarque, Edmond J., Vroegrijk, Irene O.C.M., van Duinen, Sjoerd G., Thomas, Alan W., Khan, Shahid M., Mann, Matthias, Kocken, Clemens H.M., Janse, Chris J., Franke-Fayard, Blandine M.D.
Published 2012

Correction: MVA.85A Boosting of BCG and an Attenuated, phoP Deficient M. tuberculosis Vaccine Both Show Protective Efficacy Against Tuberculosis in Rhesus Macaques

by Verreck, Frank A. W., Vervenne, Richard A. W., Kondova, Ivanela, van Kralingen, Klaas W., Remarque, Edmond J., Braskamp, Gerco, van der Werff, Nicole M., Kersbergen, Ariena, Ottenhoff, Tom H. M., Heidt, Peter J., Gilbert, Sarah C., Gicquel, Brigitte, Hill, Adrian V. S., Martin, Carlos, McShane, Helen, Thomas, Alan W.
Published 2011

Transgenic Fluorescent Plasmodium cynomolgi Liver Stages Enable Live Imaging and Purification of Malaria Hypnozoite-Forms

by Voorberg-van der Wel, Annemarie, Zeeman, Anne-Marie, van Amsterdam, Sandra M., van den Berg, Alexander, Klooster, Els J., Iwanaga, Shiroh, Janse, Chris J., van Gemert, Geert-Jan, Sauerwein, Robert, Beenhakker, Niels, Koopman, Gerrit, Thomas, Alan W., Kocken, Clemens H. M.
Published 2013

KAI407, a Potent Non-8-Aminoquinoline Compound That Kills Plasmodium cynomolgi Early Dormant Liver Stage Parasites In Vitro

by Zeeman, Anne-Marie, van Amsterdam, Sandra M., McNamara, Case W., Voorberg-van der Wel, Annemarie, Klooster, Els J., van den Berg, Alexander, Remarque, Edmond J., Plouffe, David M., van Gemert, Geert-Jan, Luty, Adrian, Sauerwein, Robert, Gagaring, Kerstin, Borboa, Rachel, Chen, Zhong, Kuhen, Kelli, Glynne, Richard J., Chatterjee, Arnab K., Nagle, Advait, Roland, Jason, Winzeler, Elizabeth A., Leroy, Didier, Campo, Brice, Diagana, Thierry T., Yeung, Bryan K. S., Thomas, Alan W., Kocken, Clemens H. M.
Published 2014