Recent Developments in Drug Discovery for Leishmaniasis and Human African Trypanosomiasis

by Nagle, Advait S., Khare, Shilpi, Kumar, Arun Babu, Supek, Frantisek, Buchynskyy, Andriy, Mathison, Casey J. N., Chennamaneni, Naveen Kumar, Pendem, Nagendar, Buckner, Frederick S., Gelb, Michael H., Molteni, Valentina
Published 2014

Cell-based optimization of novel benzamides as potential antimalarial leads

by Wu, Tao, Nagle, Advait, Sakata, Tomoyo, Henson, Kerstin, Borboa, Rachel, Chen, Zhong, Kuhen, Kelli, Plouffe, David, Winzeler, Elizabeth, Adrian, Francisco, Tuntland, Tove, Chang, Jonathan, Simerson, Susan, Howard, Steven, Ek, Jared, Isbell, John, Deng, Xianming, Gray, Nathanael S., Tully, David C., Chatterjee, Arnab K.
Published 2009

Imidazolopiperazines: Lead Optimization of the Second-Generation Antimalarial Agents

by Nagle, Advait, Wu, Tao, Kuhen, Kelli, Gagaring, Kerstin, Borboa, Rachel, Francek, Caroline, Chen, Zhong, Plouffe, David, Lin, Xuena, Caldwell, Christopher, Ek, Jared, Skolnik, Suzanne, Liu, Fenghua, Wang, Jianling, Chang, Jonathan, Li, Chun, Liu, Bo, Hollenbeck, Thomas, Tuntland, Tove, Isbell, John, Chuan, Tiffany, Alper, Philip B., Fischli, Christoph, Brun, Reto, Lakshminarayana, Suresh B., Rottmann, Matthias, Diagana, Thierry T., Winzeler, Elizabeth A., Glynne, Richard, Tully, David C., Chatterjee, Arnab K.
Published 2012

KAI407, a Potent Non-8-Aminoquinoline Compound That Kills Plasmodium cynomolgi Early Dormant Liver Stage Parasites In Vitro

by Zeeman, Anne-Marie, van Amsterdam, Sandra M., McNamara, Case W., Voorberg-van der Wel, Annemarie, Klooster, Els J., van den Berg, Alexander, Remarque, Edmond J., Plouffe, David M., van Gemert, Geert-Jan, Luty, Adrian, Sauerwein, Robert, Gagaring, Kerstin, Borboa, Rachel, Chen, Zhong, Kuhen, Kelli, Glynne, Richard J., Chatterjee, Arnab K., Nagle, Advait, Roland, Jason, Winzeler, Elizabeth A., Leroy, Didier, Campo, Brice, Diagana, Thierry T., Yeung, Bryan K. S., Thomas, Alan W., Kocken, Clemens H. M.
Published 2014

Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum

by Vaidya, Akhil B., Morrisey, Joanne M., Zhang, Zhongsheng, Das, Sudipta, Daly, Thomas M., Otto, Thomas D., Spillman, Natalie J., Wyvratt, Matthew, Siegl, Peter, Marfurt, Jutta, Wirjanata, Grennady, Sebayang, Boni F., Price, Ric N., Chatterjee, Arnab, Nagle, Advait, Stasiak, Marcin, Charman, Susan A., Angulo-Barturen, Iñigo, Ferrer, Santiago, Belén Jiménez-Díaz, María, Martínez, María Santos, Gamo, Francisco Javier, Avery, Vicky M., Ruecker, Andrea, Delves, Michael, Kirk, Kiaran, Berriman, Matthew, Kortagere, Sandhya, Burrows, Jeremy, Fan, Erkang, Bergman, Lawrence W.
Published 2014

Targeting Plasmodium phosphatidylinositol 4-kinase to eliminate malaria

by McNamara, Case W, Lee, Marcus CS, Lim, Chek Shik, Lim, Siau Hoi, Roland, Jason, Simon, Oliver, Yeung, Bryan KS, Chatterjee, Arnab K, McCormack, Susan L, Manary, Micah J, Zeeman, Anne-Marie, Dechering, Koen J, Kumar, TR Santha, Henrich, Philipp P, Gagaring, Kerstin, Ibanez, Maureen, Kato, Nobutaka, Kuhen, Kelli L, Fischli, Christoph, Nagle, Advait, Rottmann, Matthias, Plouffe, David M, Bursulaya, Badry, Meister, Stephan, Rameh, Lucia, Trappe, Joerg, Haasen, Dorothea, Timmerman, Martijn, Sauerwein, Robert W, Suwanarusk, Rossarin, Russell, Bruce, Renia, Laurent, Nosten, Francois, Tully, David C, Kocken, Clemens HM, Glynne, Richard J, Bodenreider, Christophe, Fidock, David A, Diagana, Thierry T, Winzeler, Elizabeth A
Published 2013

Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness

by Khare, Shilpi, Nagle, Advait S., Biggart, Agnes, Lai, Yin H., Liang, Fang, Davis, Lauren C., Barnes, S. Whitney, Mathison, Casey J. N., Myburgh, Elmarie, Gao, Mu-Yun, Gillespie, J. Robert, Liu, Xianzhong, Tan, Jocelyn L., Stinson, Monique, Rivera, Ianne C., Ballard, Jaime, Yeh, Vince, Groessl, Todd, Federe, Glenn, Koh, Hazel X. Y., Venable, John D., Bursulaya, Badry, Shapiro, Michael, Mishra, Pranab K., Spraggon, Glen, Brock, Ansgar, Mottram, Jeremy C., Buckner, Frederick S., Rao, Srinivasa P. S., Wen, Ben G., Walker, John R., Tuntland, Tove, Molteni, Valentina, Glynne, Richard J., Supek, Frantisek
Published 2016

KAF156 Is an Antimalarial Clinical Candidate with Potential for Use in Prophylaxis, Treatment, and Prevention of Disease Transmission

by Kuhen, Kelli L., Chatterjee, Arnab K., Rottmann, Matthias, Gagaring, Kerstin, Borboa, Rachel, Buenviaje, Jennifer, Chen, Zhong, Francek, Carolyn, Wu, Tao, Nagle, Advait, Barnes, S. Whitney, Plouffe, David, Lee, Marcus C. S., Fidock, David A., Graumans, Wouter, van de Vegte-Bolmer, Marga, van Gemert, Geert J., Wirjanata, Grennady, Sebayang, Boni, Marfurt, Jutta, Russell, Bruce, Suwanarusk, Rossarin, Price, Ric N., Nosten, Francois, Tungtaeng, Anchalee, Gettayacamin, Montip, Sattabongkot, Jetsumon, Taylor, Jennifer, Walker, John R., Tully, David, Patra, Kailash P., Flannery, Erika L., Vinetz, Joseph M., Renia, Laurent, Sauerwein, Robert W., Winzeler, Elizabeth A., Glynne, Richard J., Diagana, Thierry T.
Published 2014