Long Term Protection after Immunization with P. berghei Sporozoites Correlates with Sustained IFNγ Responses of Hepatic CD8+ Memory T Cells

by Nganou-Makamdop, Krystelle, van Gemert, Geert-Jan, Arens, Theo, Hermsen, Cornelus C., Sauerwein, Robert W.
Published 2012

Evaluation of immunity against malaria using luciferase-expressing Plasmodium berghei parasites

by Ploemen, Ivo, Behet, Marije, Nganou-Makamdop, Krystelle, van Gemert, Geert-Jan, Bijker, Else, Hermsen, Cornelus, Sauerwein, Robert
Published 2011

Molecular detection and quantification of Plasmodium falciparum-infected human hepatocytes in chimeric immune-deficient mice

by Foquet, Lander, Hermsen, Cornelus C, van Gemert, Geert-Jan, Libbrecht, Louis, Sauerwein, Robert, Meuleman, Philip, Leroux-Roels, Geert
Published 2013

Studying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malaria

by Bijker, Else M, Nganou-Makamdop, Krystelle, van Gemert, Geert-Jan, Zavala, Fidel, Cockburn, Ian, Sauerwein, Robert W
Published 2015

Bacterium-like particles as multi-epitope delivery platform for Plasmodium berghei circumsporozoite protein induce complete protection against malaria in mice

by Nganou-Makamdop, Krystelle, van Roosmalen, Maarten L, Audouy, Sandrine AL, van Gemert, Geert-Jan, Leenhouts, Kees, Hermsen, Cornelus C, Sauerwein, Robert W
Published 2012

Malaria Infected Mosquitoes Express Enhanced Attraction to Human Odor

by Smallegange, Renate C., van Gemert, Geert-Jan, van de Vegte-Bolmer, Marga, Gezan, Salvador, Takken, Willem, Sauerwein, Robert W., Logan, James G.
Published 2013

Plasmodium berghei Δp52&p36 Parasites Develop Independent of a Parasitophorous Vacuole Membrane in Huh-7 Liver Cells

by Ploemen, Ivo H. J., Croes, Huib J., van Gemert, Geert-Jan J., Wijers-Rouw, Mietske, Hermsen, Cornelus C., Sauerwein, Robert W.
Published 2012

A semi-automated luminescence based standard membrane feeding assay identifies novel small molecules that inhibit transmission of malaria parasites by mosquitoes

by Vos, Martijn W., Stone, Will J. R., Koolen, Karin M., van Gemert, Geert-Jan, van Schaijk, Ben, Leroy, Didier, Sauerwein, Robert W., Bousema, Teun, Dechering, Koen J.
Published 2015

Transmission-blocking activity of antibodies to Plasmodium falciparum GLURP.10C chimeric protein formulated in different adjuvants

by Roeffen, Will, Theisen, Michael, van de Vegte-Bolmer, Marga, van Gemert, GeertJan, Arens, Theo, Andersen, Gorm, Christiansen, Michael, Sevargave, Laxman, Singh, Shrawan Kumar, Kaviraj, Swarnendu, Sauerwein, Robert
Published 2015

Sporozoite immunization of human volunteers under chemoprophylaxis induces functional antibodies against pre-erythrocytic stages of Plasmodium falciparum

by Behet, Marije C, Foquet, Lander, van Gemert, Geert-Jan, Bijker, Else M, Meuleman, Philip, Leroux-Roels, Geert, Hermsen, Cornelus C, Scholzen, Anja, Sauerwein, Robert W
Published 2014

Towards an In Vitro Model of Plasmodium Hypnozoites Suitable for Drug Discovery

by Dembele, Laurent, Gego, Audrey, Zeeman, Anne-Marie, Franetich, Jean-François, Silvie, Olivier, Rametti, Armelle, Le Grand, Roger, Dereuddre-Bosquet, Nathalie, Sauerwein, Robert, van Gemert, Geert-Jan, Vaillant, Jean-Christophe, Thomas, Alan W., Snounou, Georges, Kocken, Clemens H. M., Mazier, Dominique
Published 2011

Immunization with genetically attenuated P52-deficient Plasmodium berghei sporozoites induces a long-lasting effector memory CD8+ T cell response in the liver

by Douradinha, Bruno, van Dijk, Melissa, van Gemert, Geert-Jan, Khan, Shahid M, Janse, Chris J, Waters, Andy P, Sauerwein, Robert W, Luty, Adrian JF, Silva-Santos, Bruno, Mota, Maria M, Epiphanio, Sabrina
Published 2011

The relevance and applicability of oocyst prevalence as a read-out for mosquito feeding assays

by Stone, Will J. R., Eldering, Maarten, van Gemert, Geert-Jan, Lanke, Kjerstin H. W., Grignard, Lynn, van de Vegte-Bolmer, Marga G., Siebelink-Stoter, Rianne, Graumans, Wouter, Roeffen, Will F. G., Drakeley, Chris J., Sauerwein, Robert W., Bousema, Teun
Published 2013

An inter-laboratory comparison of standard membrane-feeding assays for evaluation of malaria transmission-blocking vaccines

by Miura, Kazutoyo, Stone, Will J. R., Koolen, Karin M., Deng, Bingbing, Zhou, Luwen, van Gemert, Geert-Jan, Locke, Emily, Morin, Merribeth, Bousema, Teun, Sauerwein, Robert W., Long, Carole A., Dechering, Koen J.
Published 2016

Heterologous Protection against Malaria after Immunization with Plasmodium falciparum Sporozoites

by Schats, Remko, Bijker, Else M., van Gemert, Geert-Jan, Graumans, Wouter, van de Vegte-Bolmer, Marga, van Lieshout, Lisette, Haks, Mariëlle C., Hermsen, Cornelus C., Scholzen, Anja, Visser, Leo G., Sauerwein, Robert W.
Published 2015

Variation in susceptibility of African Plasmodium falciparum malaria parasites to TEP1 mediated killing in Anopheles gambiae mosquitoes

by Eldering, Maarten, Morlais, Isabelle, van Gemert, Geert-Jan, van de Vegte-Bolmer, Marga, Graumans, Wouter, Siebelink-Stoter, Rianne, Vos, Martijn, Abate, Luc, Roeffen, Will, Bousema, Teun, Levashina, Elena A., Sauerwein, Robert W.
Published 2016

Cytotoxic Markers Associate With Protection Against Malaria in Human Volunteers Immunized With Plasmodium falciparum Sporozoites

by Bijker, Else M., Teirlinck, Anne C., Schats, Remko, van Gemert, Geert-Jan, van de Vegte-Bolmer, Marga, van Lieshout, Lisette, IntHout, Joanna, Hermsen, Cornelus C., Scholzen, Anja, Visser, Leo G., Sauerwein, Robert W.
Published 2014

Transgenic Fluorescent Plasmodium cynomolgi Liver Stages Enable Live Imaging and Purification of Malaria Hypnozoite-Forms

by Voorberg-van der Wel, Annemarie, Zeeman, Anne-Marie, van Amsterdam, Sandra M., van den Berg, Alexander, Klooster, Els J., Iwanaga, Shiroh, Janse, Chris J., van Gemert, Geert-Jan, Sauerwein, Robert, Beenhakker, Niels, Koopman, Gerrit, Thomas, Alan W., Kocken, Clemens H. M.
Published 2013

Safety, Immunogenicity, and Protective Efficacy of Intradermal Immunization with Aseptic, Purified, Cryopreserved Plasmodium falciparum Sporozoites in Volunteers under Chloroquine...

by Bastiaens, Guido J. H., van Meer, Maurits P. A., Scholzen, Anja, Obiero, Joshua M., Vatanshenassan, Mansoureh, van Grinsven, Tim, Kim Lee Sim, B., Billingsley, Peter F., James, Eric R., Gunasekera, Anusha, Bijker, Else M., van Gemert, Geert-Jan, van de Vegte-Bolmer, Marga, Graumans, Wouter, Hermsen, Cornelus C., de Mast, Quirijn, van der Ven, André J. A. M., Hoffman, Stephen L., Sauerwein, Robert W.
Published 2016

Sporozoite Immunization of Human Volunteers under Mefloquine Prophylaxis Is Safe, Immunogenic and Protective: A Double-Blind Randomized Controlled Clinical Trial

by Bijker, Else M., Schats, Remko, Obiero, Joshua M., Behet, Marije C., van Gemert, Geert-Jan, van de Vegte-Bolmer, Marga, Graumans, Wouter, van Lieshout, Lisette, Bastiaens, Guido J. H., Teelen, Karina, Hermsen, Cornelus C., Scholzen, Anja, Visser, Leo G., Sauerwein, Robert W.
Published 2014