A New In Vivo Screening Paradigm to Accelerate Antimalarial Drug Discovery

by Jiménez-Díaz, María Belén, Viera, Sara, Ibáñez, Javier, Mulet, Teresa, Magán-Marchal, Noemí, Garuti, Helen, Gómez, Vanessa, Cortés-Gil, Lorena, Martínez, Antonio, Ferrer, Santiago, Fraile, María Teresa, Calderón, Félix, Fernández, Esther, Shultz, Leonard D., Leroy, Didier, Wilson, David M., García-Bustos, José Francisco, Gamo, Francisco Javier, Angulo-Barturen, Iñigo
Published 2013

Linking Murine and Human Plasmodium falciparum Challenge Models in a Translational Path for Antimalarial Drug Development

by McCarthy, James S., Marquart, Louise, Sekuloski, Silvana, Trenholme, Katharine, Elliott, Suzanne, Griffin, Paul, Rockett, Rebecca, O'Rourke, Peter, Sloots, Theo, Angulo-Barturen, Iñigo, Ferrer, Santiago, Jiménez-Díaz, María Belén, Martínez, María-Santos, van Huijsduijnen, Rob Hooft, Duparc, Stephan, Leroy, Didier, Wells, Timothy N. C., Baker, Mark, Möhrle, Jörg J.
Published 2016

Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum

by Vaidya, Akhil B., Morrisey, Joanne M., Zhang, Zhongsheng, Das, Sudipta, Daly, Thomas M., Otto, Thomas D., Spillman, Natalie J., Wyvratt, Matthew, Siegl, Peter, Marfurt, Jutta, Wirjanata, Grennady, Sebayang, Boni F., Price, Ric N., Chatterjee, Arnab, Nagle, Advait, Stasiak, Marcin, Charman, Susan A., Angulo-Barturen, Iñigo, Ferrer, Santiago, Belén Jiménez-Díaz, María, Martínez, María Santos, Gamo, Francisco Javier, Avery, Vicky M., Ruecker, Andrea, Delves, Michael, Kirk, Kiaran, Berriman, Matthew, Kortagere, Sandhya, Burrows, Jeremy, Fan, Erkang, Bergman, Lawrence W.
Published 2014

Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials

by Norcross, Neil R., Baragaña, Beatriz, Wilson, Caroline, Hallyburton, Irene, Osuna-Cabello, Maria, Norval, Suzanne, Riley, Jennifer, Stojanovski, Laste, Simeons, Frederick R. C., Porzelle, Achim, Grimaldi, Raffaella, Wittlin, Sergio, Duffy, Sandra, Avery, Vicky M., Meister, Stephan, Sanz, Laura, Jiménez-Díaz, Belén, Angulo-Barturen, Iñigo, Ferrer, Santiago, Martínez, María Santos, Gamo, Francisco Javier, Frearson, Julie A., Gray, David W., Fairlamb, Alan H., Winzeler, Elizabeth A., Waterson, David, Campbell, Simon F., Willis, Paul, Read, Kevin D., Gilbert, Ian H.
Published 2016

Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose–Efficacy Modeling

by Le Bihan, Amélie, de Kanter, Ruben, Angulo-Barturen, Iñigo, Binkert, Christoph, Boss, Christoph, Brun, Reto, Brunner, Ralf, Buchmann, Stephan, Burrows, Jeremy, Dechering, Koen J., Delves, Michael, Ewerling, Sonja, Ferrer, Santiago, Fischli, Christoph, Gamo–Benito, Francisco Javier, Gnädig, Nina F., Heidmann, Bibia, Jiménez-Díaz, María Belén, Leroy, Didier, Martínez, Maria Santos, Meyer, Solange, Moehrle, Joerg J., Ng, Caroline L., Noviyanti, Rintis, Ruecker, Andrea, Sanz, Laura María, Sauerwein, Robert W., Scheurer, Christian, Schleiferboeck, Sarah, Sinden, Robert, Snyder, Christopher, Straimer, Judith, Wirjanata, Grennady, Marfurt, Jutta, Price, Ric N., Weller, Thomas, Fischli, Walter, Fidock, David A., Clozel, Martine, Wittlin, Sergio
Published 2016