WIP1 and senescence: Oxygen matters

by Olcina, Monica M, Hammond, Ester M
Published 2014

ATM activation in hypoxia - causes and consequences

by Olcina, Monica M, Grand, Roger JA, Hammond, Ester M
Published 2014

Epigenetic Therapy for Solid Tumors: Highlighting the Impact of Tumor Hypoxia

by Ramachandran, Shaliny, Ient, Jonathan, Göttgens, Eva-Leonne, Krieg, Adam J., Hammond, Ester M.
Published 2015

The Role of the HIF-1α Transcription Factor in Increased Cell Division at Physiological Oxygen Tensions

by Carrera, Samantha, Senra, Joana, Acosta, Maria Isabel, Althubiti, Mohammad, Hammond, Ester M., de Verdier, Petra J., Macip, Salvador
Published 2014

A novel method for autophagy detection in primary cells: Impaired levels of macroautophagy in immunosenescent T cells

by Phadwal, Kanchan, Alegre-Abarrategui, Javier, Watson, Alexander Scarth, Pike, Luke, Anbalagan, Selvakumar, Hammond, Ester M., Wade-Martins, Richard, McMichael, Andrew, Klenerman, Paul, Simon, Anna Katharina
Published 2012

CH-01 is a Hypoxia-Activated Prodrug That Sensitizes Cells to Hypoxia/Reoxygenation Through Inhibition of Chk1 and Aurora A

by Cazares-Körner, Cindy, Pires, Isabel M., Swallow, I. Diane, Grayer, Samuel C., O’Connor, Liam J., Olcina, Monica M., Christlieb, Martin, Conway, Stuart J., Hammond, Ester M.
Published 2013

Replication Stress and Chromatin Context Link ATM Activation to a Role in DNA Replication

by Olcina, Monica M., Foskolou, Iosifina P., Anbalagan, Selvakumar, Senra, Joana M., Pires, Isabel M., Jiang, Yanyan, Ryan, Anderson J., Hammond, Ester M.
Published 2013

Hypoxia Potentiates the Radiation-Sensitizing Effect of Olaparib in Human Non-Small Cell Lung Cancer Xenografts by Contextual Synthetic Lethality

by Jiang, Yanyan, Verbiest, Tom, Devery, Aoife M., Bokobza, Sivan M., Weber, Anika M., Leszczynska, Katarzyna B., Hammond, Ester M., Ryan, Anderson J.
Published 2016

Preclinical testing of an Atr inhibitor demonstrates improved response to standard therapies for esophageal cancer

by Leszczynska, Katarzyna B., Dobrynin, Greg, Leslie, Rhea E., Ient, Jonathan, Boumelha, Adam J., Senra, Joana M., Hawkins, Maria A., Maughan, Tim, Mukherjee, Somnath, Hammond, Ester M.
Published 2016

Mechanisms and consequences of ATMIN repression in hypoxic conditions: roles for p53 and HIF-1

by Leszczynska, Katarzyna B., Göttgens, Eva-Leonne, Biasoli, Deborah, Olcina, Monica M., Ient, Jonathan, Anbalagan, Selvakumar, Bernhardt, Stephan, Giaccia, Amato J., Hammond, Ester M.
Published 2016

The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia

by Ashton, Thomas M., Fokas, Emmanouil, Kunz-Schughart, Leoni A., Folkes, Lisa K., Anbalagan, Selvakumar, Huether, Melanie, Kelly, Catherine J., Pirovano, Giacomo, Buffa, Francesca M., Hammond, Ester M., Stratford, Michael, Muschel, Ruth J., Higgins, Geoff S., McKenna, William Gillies
Published 2016

Optimization of 3,5-Dimethylisoxazole Derivatives as Potent Bromodomain Ligands

by Hewings, David S., Fedorov, Oleg, Filippakopoulos, Panagis, Martin, Sarah, Picaud, Sarah, Tumber, Anthony, Wells, Christopher, Olcina, Monica M., Freeman, Katherine, Gill, Andrew, Ritchie, Alison J., Sheppard, David W., Russell, Angela J., Hammond, Ester M., Knapp, Stefan, Brennan, Paul E., Conway, Stuart J.
Published 2013

UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1α

by Goto, Yoko, Zeng, Lihua, Yeom, Chan Joo, Zhu, Yuxi, Morinibu, Akiyo, Shinomiya, Kazumi, Kobayashi, Minoru, Hirota, Kiichi, Itasaka, Satoshi, Yoshimura, Michio, Tanimoto, Keiji, Torii, Masae, Sowa, Terumasa, Menju, Toshi, Sonobe, Makoto, Kakeya, Hideaki, Toi, Masakazu, Date, Hiroshi, Hammond, Ester M., Hiraoka, Masahiro, Harada, Hiroshi
Published 2015