3,5-Dimethylisoxazoles Act As Acetyl-lysine-mimetic Bromodomain Ligands

by Hewings, David S., Wang, Minghua, Philpott, Martin, Fedorov, Oleg, Uttarkar, Sagar, Filippakopoulos, Panagis, Picaud, Sarah, Vuppusetty, Chaitanya, Marsden, Brian, Knapp, Stefan, Conway, Stuart J., Heightman, Tom D.
Published 2011

Organocatalytic Removal of Formaldehyde Adducts from RNA and DNA Bases

by Karmakar, Saswata, Harcourt, Emily M., Hewings, David S., Lovejoy, Alexander F., Kurtz, David M., Ehrenschwender, Thomas, Barandun, Luzi J., Roost, Caroline, Alizadeh, Ash A., Kool, Eric T.
Published 2015

Isoxazole‐Derived Amino Acids are Bromodomain‐Binding Acetyl‐Lysine Mimics: Incorporation into Histone H4 Peptides and Histone H3

by Sekirnik (née Measures), Angelina R., Hewings, David S., Theodoulou, Natalie H., Jursins, Lukass, Lewendon, Katie R., Jennings, Laura E., Rooney, Timothy P. C., Heightman, Tom D., Conway, Stuart J.
Published 2016

Optimization of 3,5-Dimethylisoxazole Derivatives as Potent Bromodomain Ligands

by Hewings, David S., Fedorov, Oleg, Filippakopoulos, Panagis, Martin, Sarah, Picaud, Sarah, Tumber, Anthony, Wells, Christopher, Olcina, Monica M., Freeman, Katherine, Gill, Andrew, Ritchie, Alison J., Sheppard, David W., Russell, Angela J., Hammond, Ester M., Knapp, Stefan, Brennan, Paul E., Conway, Stuart J.
Published 2013