ATM activation in hypoxia - causes and consequences
The DNA damage response is a complex signaling cascade that is triggered by cellular stress. This response is essential for the maintenance of genomic integrity and is considered to act as a barrier to the early stages of tumorigenesis. The integral role of ataxia telangiectasia mutated (ATM) kinase...
Main Authors: | , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Taylor & Francis
2014
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905164/ |