Frequency of glucose-6-phosphate dehydrogenase deficiency in malaria patients from six African countries enrolled in two randomized anti-malarial clinical trials

by Carter, Nick, Pamba, Allan, Duparc, Stephan, Waitumbi, John N
Published 2011

Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration

by Morris, Carrie A, Duparc, Stephan, Borghini-Fuhrer, Isabelle, Jung, Donald, Shin, Chang-Sik, Fleckenstein, Lawrence
Published 2011

Creative solutions to extraordinary challenges in clinical trials: methodology of a phase III trial of azithromycin and chloroquine fixed-dose combination in pregnant women in Afri...

by Chandra, Richa S, Orazem, John, Ubben, David, Duparc, Stephan, Robbins, Jeffery, Vandenbroucke, Pol
Published 2013

The global pipeline of new medicines for the control and elimination of malaria

by Anthony, Melinda P, Burrows, Jeremy N, Duparc, Stephan, JMoehrle, Joerg, Wells, Timothy NC
Published 2012

Diagnosis and Treatment of Plasmodium vivax Malaria

by Baird, J. Kevin, Valecha, Neena, Duparc, Stephan, White, Nicholas J., Price, Ric N.
Published 2016

Evaluation of the QT effect of a combination of piperaquine and a novel anti-malarial drug candidate OZ439, for the treatment of uncomplicated malaria

by Darpo, Borje, Ferber, Georg, Siegl, Peter, Laurijssens, Bart, Macintyre, Fiona, Toovey, Stephen, Duparc, Stephan
Published 2015

Safety and efficacy of pyronaridine-artesunate in uncomplicated acute malaria: an integrated analysis of individual patient data from six randomized clinical trials

by Duparc, Stephan, Borghini-Fuhrer, Isabelle, Craft, Carl J, Arbe-Barnes, Sarah, Miller, Robert M, Shin, Chang-Sik, Fleckenstein, Lawrence
Published 2013

Efficacy and Safety of Azithromycin-Chloroquine versus Sulfadoxine-Pyrimethamine for Intermittent Preventive Treatment of Plasmodium falciparum Malaria Infection in Pregnant Women...

by Kimani, Joshua, Phiri, Kamija, Kamiza, Steve, Duparc, Stephan, Ayoub, Ayman, Rojo, Ricardo, Robbins, Jeffery, Orrico, Russell, Vandenbroucke, Pol
Published 2016

Parasitological Clearance Rates and Drug Concentrations of a Fixed Dose Combination of Azithromycin-Chloroquine in Asymptomatic Pregnant Women with Plasmodium Falciparum Parasitemi...

by Phiri, Kamija, Kimani, Joshua, Mtove, George A., Zhao, Qinying, Rojo, Ricardo, Robbins, Jeffery, Duparc, Stephan, Ayoub, Ayman, Vandenbroucke, Pol
Published 2016

Delayed Anemia after Treatment with Injectable Artesunate in the Democratic Republic of the Congo: A Manageable Issue

by Burri, Christian, Ferrari, Giovanfrancesco, Ntuku, Henry Maggi, Kitoto, Antoinette Tshefu, Duparc, Stephan, Hugo, Pierre, Mitembo, Didier Kalemwa, Lengeler, Christian
Published 2014

Drug-Drug Interaction Analysis of Pyronaridine/Artesunate and Ritonavir in Healthy Volunteers

by Morris, Carrie A., Lopez-Lazaro, Luis, Jung, Donald, Methaneethorn, Janthima, Duparc, Stephan, Borghini-Fuhrer, Isabelle, Pokorny, Rolf, Shin, Chang-Sik, Fleckenstein, Lawrence
Published 2012

First-in-man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials

by Moehrle, Joerg J, Duparc, Stephan, Siethoff, Christoph, Giersbergen, Paul L M, Craft, J Carl, Arbe-Barnes, Sarah, Charman, Susan A, Gutierrez, Maria, Wittlin, Sergio, Vennerstrom, Jonathan L
Published 2013

Review of pyronaridine anti-malarial properties and product characteristics

by Croft, Simon L, Duparc, Stephan, Arbe-Barnes, Sarah J, Craft, J Carl, Shin, Chang-Sik, Fleckenstein, Lawrence, Borghini-Fuhrer, Isabelle, Rim, Han-Jong
Published 2012

Pharmacokinetic Interactions between Tafenoquine and Dihydroartemisinin-Piperaquine or Artemether-Lumefantrine in Healthy Adult Subjects

by Green, Justin A., Mohamed, Khadeeja, Goyal, Navin, Bouhired, Samia, Hussaini, Azra, Jones, Siôn W., Koh, Gavin C. K. W., Kostov, Ivan, Taylor, Maxine, Wolstenholm, Allen, Duparc, Stephan
Published 2016

Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: an open-label phase...

by Phyo, Aung Pyae, Jittamala, Podjanee, Nosten, François H, Pukrittayakamee, Sasithon, Imwong, Mallika, White, Nicholas J, Duparc, Stephan, Macintyre, Fiona, Baker, Mark, Möhrle, Jörg J
Published 2016

Population Pharmacokinetics of Pyronaridine in Pediatric Malaria Patients

by Ayyoub, Amal, Methaneethorn, Janthima, Ramharter, Michael, Djimde, Abdoulaye A., Tekete, Mamadou, Duparc, Stephan, Borghini-Fuhrer, Isabelle, Shin, Jang-Sik, Fleckenstein, Lawrence
Published 2016

Pharmacokinetic Interaction between Pyronaridine-Artesunate and Metoprolol

by Morris, Carrie A., Pokorny, Rolf, Lopez-Lazaro, Luis, Miller, Robert M., Arbe-Barnes, Sarah, Duparc, Stephan, Borghini-Fuhrer, Isabelle, Shin, Jang-Sik, Fleckenstein, Lawrence
Published 2014

Tafenoquine at therapeutic concentrations does not prolong fridericia-corrected QT interval in healthy subjects

by Green, Justin A, Patel, Apurva K, Patel, Bela R, Hussaini, Azra, Harrell, Emma J, McDonald, Mirna J, Carter, Nick, Mohamed, Khadeeja, Duparc, Stephan, Miller, Ann K
Published 2014

Chlorproguanil−Dapsone−Artesunate versus Artemether−Lumefantrine: A Randomized, Double-Blind Phase III Trial in African Children and Adolescents with Uncomplicated Plasmodium falci...

by Premji, Zul, Umeh, Rich E., Owusu-Agyei, Seth, Esamai, Fabian, Ezedinachi, Emmanuel U., Oguche, Stephen, Borrmann, Steffen, Sowunmi, Akintunde, Duparc, Stephan, Kirby, Paula L., Pamba, Allan, Kellam, Lynda, Guiguemdé, Robert, Greenwood, Brian, Ward, Stephen A., Winstanley, Peter A.
Published 2009

A Pilot Randomised Trial of Induced Blood-Stage Plasmodium falciparum Infections in Healthy Volunteers for Testing Efficacy of New Antimalarial Drugs

by McCarthy, James S., Sekuloski, Silvana, Griffin, Paul M., Elliott, Suzanne, Douglas, Nanette, Peatey, Chris, Rockett, Rebecca, O'Rourke, Peter, Marquart, Louise, Hermsen, Cornelius, Duparc, Stephan, Möhrle, Jörg, Trenholme, Katharine R., Humberstone, Andrew J.
Published 2011