Quantitative cross-linking/mass spectrometry reveals subtle protein conformational changes

Quantitative cross-linking/mass spectrometry reveals subtle protein conformational changes

Quantitative cross-linking/mass spectrometry (QCLMS) probes protein structural dynamics in solution by quantitatively comparing the yields of cross-links between different conformational statuses. We have used QCLMS to understand the final maturation step of the proteasome lid and also to elucidate...

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Bibliographic Details
Main Authors: Chen, Zhuo, Fischer, Lutz, Tahir, Salman, Bukowski-Wills, Jimi-Carlo, Barlow, Paul, Rappsilber, Juri
Format: Online
Language:English
Published: F1000Research 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140025/

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