Quantitative cross-linking/mass spectrometry reveals subtle protein conformational changes
Quantitative cross-linking/mass spectrometry (QCLMS) probes protein structural dynamics in solution by quantitatively comparing the yields of cross-links between different conformational statuses. We have used QCLMS to understand the final maturation step of the proteasome lid and also to elucidate...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
F1000Research
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140025/ |