Retention of acetylcarnitine in chronic kidney disease causes insulin resistance in skeletal muscle

Retention of acetylcarnitine in chronic kidney disease causes insulin resistance in skeletal muscle

Insulin resistance occurs frequently in patients with chronic kidney disease. However, the mechanisms of insulin resistance associated with chronic kidney disease are unclear. It is known that an increase in the mitochondrial acetyl-CoA (AcCoA)/CoA ratio causes insulin resistance in skeletal muscle,...

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Bibliographic Details
Main Authors:	Miyamoto, Yasunori, Miyazaki, Teruo, Honda, Akira, Shimohata, Homare, Hirayama, Kouichi, Kobayashi, Masaki
Format:	Online
Language:	English
Published:	the Society for Free Radical Research Japan 2016
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110933/

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