Calpain-10 and insulin resistance in human skeletal muscle

Variation in the calpain-10 gene has been linked to a three-fold increased risk for type 2 diabetes in Pima Indian and some European populations. Furthermore, reduced skeletal muscle expression of calpain-10 is associated with reduced insulin mediated glucose disposal and carbohydrate oxidation. T...

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Bibliographic Details
Main Author: Norton, Luke
Format: Thesis (University of Nottingham only)
Language:English
Published: 2007
Online Access:http://eprints.nottingham.ac.uk/11536/
http://eprints.nottingham.ac.uk/11536/1/Thesis_final.pdf