Retention of acetylcarnitine in chronic kidney disease causes insulin resistance in skeletal muscle
Insulin resistance occurs frequently in patients with chronic kidney disease. However, the mechanisms of insulin resistance associated with chronic kidney disease are unclear. It is known that an increase in the mitochondrial acetyl-CoA (AcCoA)/CoA ratio causes insulin resistance in skeletal muscle,...
| Main Authors: | , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
the Society for Free Radical Research Japan
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110933/ |