Acid Sphingomyelinase Mediates Oxidized-LDL Induced Apoptosis in Macrophage via Endoplasmic Reticulum Stress

Acid Sphingomyelinase Mediates Oxidized-LDL Induced Apoptosis in Macrophage via Endoplasmic Reticulum Stress

Aim: Macrophage apoptosis is a vital event in advanced atherosclerosis, and oxidized low-density lipoprotein (ox-LDL) is a major contributor to this process. Acid sphingomyelinase (ASM) and ceramide are also involved in the induction of apoptosis, particularly in macrophages. Our current study focus...

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Bibliographic Details
Main Authors:	Zhao, Min, Pan, Wei, Shi, Rui-zheng, Bai, Yong-ping, You, Bo-yang, Zhang, Kai, Fu, Qiong-mei, Schuchman, Edward H., He, Xing-xuan, Zhang, Guo-gang
Format:	Online
Language:	English
Published:	Japan Atherosclerosis Society 2016
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090817/

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