Acid Sphingomyelinase Mediates Oxidized-LDL Induced Apoptosis in Macrophage via Endoplasmic Reticulum Stress
Aim: Macrophage apoptosis is a vital event in advanced atherosclerosis, and oxidized low-density lipoprotein (ox-LDL) is a major contributor to this process. Acid sphingomyelinase (ASM) and ceramide are also involved in the induction of apoptosis, particularly in macrophages. Our current study focus...
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Bibliographic Details
| Main Authors: |
Zhao, Min,
Pan, Wei,
Shi, Rui-zheng,
Bai, Yong-ping,
You, Bo-yang,
Zhang, Kai,
Fu, Qiong-mei,
Schuchman, Edward H.,
He, Xing-xuan,
Zhang, Guo-gang |
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| Format: | Online
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| Language: | English |
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| Published: |
Japan Atherosclerosis Society
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090817/
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