Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity
The cytoskeletal adapter protein talin plays a prominent role in adhesive structures connecting integrins to the actin cytoskeleton. In this work, Kumar et al. use a novel talin sensor to measure talin tension and provide insights into focal adhesion force transmission and mechanosensitivity.
Main Authors: | Kumar, Abhishek, Ouyang, Mingxing, Van den Dries, Koen, McGhee, Ewan James, Tanaka, Keiichiro, Anderson, Marie D., Groisman, Alexander, Goult, Benjamin T., Anderson, Kurt I., Schwartz, Martin A. |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862330/ |
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