Focal adhesion kinase-dependent focal adhesion recruitment of SH2 domains directs SRC into focal adhesions to regulate cell adhesion and migration

Directed cell migration requires dynamical control of the protein complex within focal adhesions (FAs) and this control is regulated by signaling events involving tyrosine phosphorylation. We screened the SH2 domains present in tyrosine-specific kinases and phosphatases found within FAs, including S...

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Bibliographic Details
Main Authors: Wu, Jui-Chung, Chen, Yu-Chen, Kuo, Chih-Ting, Wenshin Yu, Helen, Chen, Yin-Quan, Chiou, Arthur, Kuo, Jean-Cheng
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683442/