Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity

The cytoskeletal adapter protein talin plays a prominent role in adhesive structures connecting integrins to the actin cytoskeleton. In this work, Kumar et al. use a novel talin sensor to measure talin tension and provide insights into focal adhesion force transmission and mechanosensitivity.

Bibliographic Details
Main Authors: Kumar, Abhishek, Ouyang, Mingxing, Van den Dries, Koen, McGhee, Ewan James, Tanaka, Keiichiro, Anderson, Marie D., Groisman, Alexander, Goult, Benjamin T., Anderson, Kurt I., Schwartz, Martin A.
Format: Online
Language:English
Published: The Rockefeller University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862330/