Human telomerase reverse transcriptase binds to a pre-organized hTR in vivo exposing its template
Telomerase is a specialized reverse transcriptase that is responsible for telomere length maintenance. As in other organisms, the minimal components required for an active human telomerase are the template-providing telomerase RNA (hTR) and the enzymatic entity telomerase reverse transcriptase (hTER...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705647/ |