Telomerase reverse transcriptase in the regulation of gene expression

Telomerase plays a pivotal role in the pathology of aging and cancer by maintaining genome integrity, controlling cell proliferation, and regulating tissue homeostasis. Telomerase is essentially composed of an RNA component, Telomerase RNA or TERC, which serves as a template for telomeric DNA synthe...

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Bibliographic Details
Main Authors: Zhou, Junzhi, Ding, Deqiang, Wang, Miao, Cong, Yu-Sheng
Format: Online
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163847/