Simultaneous Reprogramming and Gene Correction of Patient Fibroblasts

Simultaneous Reprogramming and Gene Correction of Patient Fibroblasts

The derivation of genetically modified induced pluripotent stem (iPS) cells typically involves multiple steps, requiring lengthy cell culture periods, drug selection, and several clonal events. We report the generation of gene-targeted iPS cell lines following a single electroporation of patient-spe...

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Bibliographic Details
Main Authors: Howden, Sara E., Maufort, John P., Duffin, Bret M., Elefanty, Andrew G., Stanley, Edouard G., Thomson, James A.
Format: Online
Language:English
Published: Elsevier 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682122/

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