Simultaneous Reprogramming and Gene Correction of Patient Fibroblasts
The derivation of genetically modified induced pluripotent stem (iPS) cells typically involves multiple steps, requiring lengthy cell culture periods, drug selection, and several clonal events. We report the generation of gene-targeted iPS cell lines following a single electroporation of patient-spe...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
Elsevier
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682122/ |