Direct Reprogramming of Mouse Fibroblasts to Neural Stem Cells by Small Molecules

Although it is possible to generate neural stem cells (NSC) from somatic cells by reprogramming technologies with transcription factors, clinical utilization of patient-specific NSC for the treatment of human diseases remains elusive. The risk hurdles are associated with viral transduction vectors i...

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Bibliographic Details
Main Authors: Han, Yan-Chuang, Lim, Yoon, Duffieldl, Michael D., Li, Hua, Liu, Jia, Abdul Manaph, Nimshitha Pavathuparambil, Yang, Miao, Keating, Damien J., Zhou, Xin-Fu
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695670/