Intraflagellar transport is essential for mammalian spermiogenesis but is absent in mature sperm
Intraflagellar transport (IFT) is necessary for the assembly and maintenance of most cilia, with the exception of gametic flagella in some organisms. IFT is required for assembly of mouse sperm flagella, and defects in IFT lead to male infertility. However, mature sperm lack IFT proteins and thus do...
Main Authors: | San Agustin, Jovenal T., Pazour, Gregory J., Witman, George B. |
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Format: | Online |
Language: | English |
Published: |
The American Society for Cell Biology
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666132/ |
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