Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly

Primary cilia are nonmotile microtubule structures that assemble from basal bodies by a process called intraflagellar transport (IFT) and are associated with several human diseases. Here, we show that the centrosome protein pericentrin (Pcnt) colocalizes with IFT proteins to the base of primary and...

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Bibliographic Details
Main Authors: Jurczyk, Agata, Gromley, Adam, Redick, Sambra, Agustin, Jovenal San, Witman, George, Pazour, Gregory J., Peters, Dorien J.M., Doxsey, Stephen
Format: Online
Language:English
Published: The Rockefeller University Press 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172416/