Intraflagellar transport is essential for mammalian spermiogenesis but is absent in mature sperm

Intraflagellar transport (IFT) is necessary for the assembly and maintenance of most cilia, with the exception of gametic flagella in some organisms. IFT is required for assembly of mouse sperm flagella, and defects in IFT lead to male infertility. However, mature sperm lack IFT proteins and thus do...

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Bibliographic Details
Main Authors: San Agustin, Jovenal T., Pazour, Gregory J., Witman, George B.
Format: Online
Language:English
Published: The American Society for Cell Biology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666132/