Dietary Intake of Sulforaphane-Rich Broccoli Sprout Extracts during Juvenile and Adolescence Can Prevent Phencyclidine-Induced Cognitive Deficits at Adulthood

Dietary Intake of Sulforaphane-Rich Broccoli Sprout Extracts during Juvenile and Adolescence Can Prevent Phencyclidine-Induced Cognitive Deficits at Adulthood

Oxidative stress and inflammation play a role in cognitive impairment, which is a core symptom of schizophrenia. Furthermore, a hallmark of the pathophysiology of this disease is the dysfunction of cortical inhibitory γ-aminobutyric acid (GABA) neurons expressing parvalbumin (PV), which is also invo...

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Main Authors: Shirai, Yumi, Fujita, Yuko, Hashimoto, Ryota, Ohi, Kazutaka, Yamamori, Hidenaga, Yasuda, Yuka, Ishima, Tamaki, Suganuma, Hiroyuki, Ushida, Yusuke, Takeda, Masatoshi, Hashimoto, Kenji
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479552/

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