Phencyclidine Disrupts the Auditory Steady State Response in Rats

The Auditory Steady-State Response (ASSR) in the electroencephalogram (EEG) is usually reduced in schizophrenia (SZ), particularly to 40 Hz stimulation. The gamma frequency ASSR deficit has been attributed to N-methyl-D-aspartate receptor (NMDAR) hypofunction. We tested whether the NMDAR antagonist,...

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Bibliographic Details
Main Authors: Leishman, Emma, O’Donnell, Brian F., Millward, James B., Vohs, Jenifer L., Rass, Olga, Krishnan, Giri P., Bolbecker, Amanda R., Morzorati, Sandra L.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530939/