Inhibition of G Protein-Activated Inwardly Rectifying K+ Channels by Phencyclidine

Addictive drugs, such as opioids, ethanol, cocaine, amphetamine, and phencyclidine (PCP), affect many functions of the nervous system and peripheral organs, resulting in severe health problems. G protein-activated inwardly rectifying K+ (GIRK, Kir3) channels play an important role in regulating neur...

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Bibliographic Details
Main Authors: Kobayashi, Toru, Nishizawa, Daisuke, Ikeda, Kazutaka
Format: Online
Language:English
Published: Bentham Science Publishers Ltd 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137191/