Performance of Genotype Imputation for Low Frequency and Rare Variants from the 1000 Genomes

Performance of Genotype Imputation for Low Frequency and Rare Variants from the 1000 Genomes

Genotype imputation is now routinely applied in genome-wide association studies (GWAS) and meta-analyses. However, most of the imputations have been run using HapMap samples as reference, imputation of low frequency and rare variants (minor allele frequency (MAF) < 5%) are not systemically assess...

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Bibliographic Details
Main Authors: Zheng, Hou-Feng, Rong, Jing-Jing, Liu, Ming, Han, Fang, Zhang, Xing-Wei, Richards, J. Brent, Wang, Li
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306552/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306552/

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