Performance of Genotype Imputation for Rare Variants Identified in Exons and Flanking Regions of Genes

Performance of Genotype Imputation for Rare Variants Identified in Exons and Flanking Regions of Genes

Genotype imputation has the potential to assess human genetic variation at a lower cost than assaying the variants using laboratory techniques. The performance of imputation for rare variants has not been comprehensively studied. We utilized 8865 human samples with high depth resequencing data for t...

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Bibliographic Details
Main Authors: Li, Li, Li, Yun, Browning, Sharon R., Browning, Brian L., Slater, Andrew J., Kong, Xiangyang, Aponte, Jennifer L., Mooser, Vincent E., Chissoe, Stephanie L., Whittaker, John C., Nelson, Matthew R., Ehm, Margaret Gelder
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176314/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176314/

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