The Empirical Power of Rare Variant Association Methods: Results from Sanger Sequencing in 1,998 Individuals

by Ladouceur, Martin, Dastani, Zari, Aulchenko, Yurii S., Greenwood, Celia M. T., Richards, J. Brent
Published 2012

Multiple Regression Methods Show Great Potential for Rare Variant Association Tests

by Xu, ChangJiang, Ladouceur, Martin, Dastani, Zari, Richards, J. Brent, Ciampi, Antonio, Greenwood, Celia M. T.
Published 2012

Obesity and Multiple Sclerosis: A Mendelian Randomization Study

by Mokry, Lauren E., Ross, Stephanie, Timpson, Nicholas J., Sawcer, Stephen, Davey Smith, George, Richards, J. Brent
Published 2016

Performance of Genotype Imputation for Low Frequency and Rare Variants from the 1000 Genomes

by Zheng, Hou-Feng, Rong, Jing-Jing, Liu, Ming, Han, Fang, Zhang, Xing-Wei, Richards, J. Brent, Wang, Li
Published 2015

Investigating causality in the association between 25(OH)D and schizophrenia

by Taylor, Amy E., Burgess, Stephen, Ware, Jennifer J., Gage, Suzanne H., Richards, J. Brent, Davey Smith, George, Munafò, Marcus R.
Published 2016

Copy number variation of the APC gene is associated with regulation of bone mineral density☆

by Chew, Shelby, Dastani, Zari, Brown, Suzanne J., Lewis, Joshua R., Dudbridge, Frank, Soranzo, Nicole, Surdulescu, Gabriela L., Richards, J. Brent, Spector, Tim D., Wilson, Scott G.
Published 2012

Genetic interactions affecting human gene expression identified by variance association mapping

by Brown, Andrew Anand, Buil, Alfonso, Viñuela, Ana, Lappalainen, Tuuli, Zheng, Hou-Feng, Richards, J Brent, Small, Kerrin S, Spector, Timothy D, Dermitzakis, Emmanouil T, Durbin, Richard
Published 2014

Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study

by Mokry, Lauren E., Ross, Stephanie, Ahmad, Omar S., Forgetta, Vincenzo, Smith, George Davey, Leong, Aaron, Greenwood, Celia M. T., Thanassoulis, George, Richards, J. Brent
Published 2015

A combined reference panel from the 1000 Genomes and UK10K projects improved rare variant imputation in European and Chinese samples

by Chou, Wen-Chi, Zheng, Hou-Feng, Cheng, Chia-Ho, Yan, Han, Wang, Li, Han, Fang, Richards, J. Brent, Karasik, David, Kiel, Douglas P., Hsu, Yi-Hsiang
Published 2016

Correction: Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study

by Mokry, Lauren E., Ross, Stephanie, Ahmad, Omar S., Forgetta, Vincenzo, Smith, George Davey, Goltzman, David, Leong, Aaron, Greenwood, Celia M. T., Thanassoulis, George, Richards, J. Brent
Published 2016

A Mendelian randomization study of the effect of type-2 diabetes on coronary heart disease

by Ahmad, Omar S., Morris, John A., Mujammami, Muhammad, Forgetta, Vincenzo, Leong, Aaron, Li, Rui, Turgeon, Maxime, Greenwood, Celia M.T., Thanassoulis, George, Meigs, James B., Sladek, Robert, Richards, J. Brent
Published 2015

Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel

by Huang, Jie, Howie, Bryan, McCarthy, Shane, Memari, Yasin, Walter, Klaudia, Min, Josine L., Danecek, Petr, Malerba, Giovanni, Trabetti, Elisabetta, Zheng, Hou-Feng, Gambaro, Giovanni, Richards, J. Brent, Durbin, Richard, Timpson, Nicholas J., Marchini, Jonathan, Soranzo, Nicole
Published 2015

Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density

by Mullin, Benjamin H., Walsh, John P., Zheng, Hou-Feng, Brown, Suzanne J., Surdulescu, Gabriela L., Curtis, Charles, Breen, Gerome, Dudbridge, Frank, Richards, J. Brent, Spector, Tim D., Wilson, Scott G.
Published 2016

The Causal Effect of Vitamin D Binding Protein (DBP) Levels on Calcemic and Cardiometabolic Diseases: A Mendelian Randomization Study

by Leong, Aaron, Rehman, Waheed, Dastani, Zari, Greenwood, Celia, Timpson, Nicholas, Langsetmo, Lisa, Berger, Claudie, Fu, Lei, Wong, Betty Y. L., Malik, Suneil, Malik, Rainer, Hanley, David A., Cole, David E. C., Goltzman, David, Richards, J. Brent
Published 2014

The Use of Genome-Wide eQTL Associations in Lymphoblastoid Cell Lines to Identify Novel Genetic Pathways Involved in Complex Traits

by Min, Josine L., Taylor, Jennifer M., Richards, J. Brent, Watts, Tim, Pettersson, Fredrik H., Broxholme, John, Ahmadi, Kourosh R., Surdulescu, Gabriela L., Lowy, Ernesto, Gieger, Christian, Newton-Cheh, Chris, Perola, Markus, Soranzo, Nicole, Surakka, Ida, Lindgren, Cecilia M., Ragoussis, Jiannis, Morris, Andrew P., Cardon, Lon R., Spector, Tim D., Zondervan, Krina T.
Published 2011

Imputation of Variants from the 1000 Genomes Project Modestly Improves Known Associations and Can Identify Low-frequency Variant - Phenotype Associations Undetected by HapMap Based...

by Wood, Andrew R., Perry, John R. B., Tanaka, Toshiko, Hernandez, Dena G., Zheng, Hou-Feng, Melzer, David, Gibbs, J. Raphael, Nalls, Michael A., Weedon, Michael N., Spector, Tim D., Richards, J. Brent, Bandinelli, Stefania, Ferrucci, Luigi, Singleton, Andrew B., Frayling, Timothy M.
Published 2013

Expression of Phosphofructokinase in Skeletal Muscle Is Influenced by Genetic Variation and Associated With Insulin Sensitivity

by Keildson, Sarah, Fadista, Joao, Ladenvall, Claes, Hedman, Åsa K., Elgzyri, Targ, Small, Kerrin S., Grundberg, Elin, Nica, Alexandra C., Glass, Daniel, Richards, J. Brent, Barrett, Amy, Nisbet, James, Zheng, Hou-Feng, Rönn, Tina, Ström, Kristoffer, Eriksson, Karl-Fredrik, Prokopenko, Inga, Spector, Timothy D., Dermitzakis, Emmanouil T., Deloukas, Panos, McCarthy, Mark I., Rung, Johan, Groop, Leif, Franks, Paul W., Lindgren, Cecilia M., Hansson, Ola
Published 2014

Genome-wide association study with 1000 genomes imputation identifies signals for nine sex hormone-related phenotypes

by Ruth, Katherine S, Campbell, Purdey J, Chew, Shelby, Lim, Ee Mun, Hadlow, Narelle, Stuckey, Bronwyn GA, Brown, Suzanne J, Feenstra, Bjarke, Joseph, John, Surdulescu, Gabriela L, Zheng, Hou Feng, Richards, J Brent, Murray, Anna, Spector, Tim D, Wilson, Scott G, Perry, John RB
Published 2016

Genetic Evidence for a Normal-Weight “Metabolically Obese” Phenotype Linking Insulin Resistance, Hypertension, Coronary Artery Disease, and Type 2 Diabetes

by Yaghootkar, Hanieh, Scott, Robert A., White, Charles C., Zhang, Weihua, Speliotes, Elizabeth, Munroe, Patricia B., Ehret, Georg B., Bis, Joshua C., Fox, Caroline S., Walker, Mark, Borecki, Ingrid B., Knowles, Joshua W., Yerges-Armstrong, Laura, Ohlsson, Claes, Perry, John R.B., Chambers, John C., Kooner, Jaspal S., Franceschini, Nora, Langenberg, Claudia, Hivert, Marie-France, Dastani, Zari, Richards, J. Brent, Semple, Robert K., Frayling, Timothy M.
Published 2014

Meta-Analysis of Genome-Wide Scans for Total Body BMD in Children and Adults Reveals Allelic Heterogeneity and Age-Specific Effects at the WNT16 Locus

by Medina-Gomez, Carolina, Kemp, John P., Estrada, Karol, Eriksson, Joel, Liu, Jeff, Reppe, Sjur, Evans, David M., Heppe, Denise H. M., Vandenput, Liesbeth, Herrera, Lizbeth, Ring, Susan M., Kruithof, Claudia J., Timpson, Nicholas J., Zillikens, M. Carola, Olstad, Ole K., Zheng, Hou-Feng, Richards, J. Brent, St. Pourcain, Beate, Hofman, Albert, Jaddoe, Vincent W. V., Smith, George Davey, Lorentzon, Mattias, Gautvik, Kaare M., Uitterlinden, André G., Brommage, Robert, Ohlsson, Claes, Tobias, Jonathan H., Rivadeneira, Fernando
Published 2012