NMDA receptor structures reveal subunit arrangement and pore architecture
N-methyl-d-aspartate (NMDA) receptors are Hebbian-like coincidence detectors, requiring binding of glycine and glutamate in combination with the relief of voltage-dependent magnesium block to open an ion conductive pore across the membrane bilayer. Despite the importance of the NMDA receptor in the...
Main Authors: | Lee, Chia-Hsueh, Lü, Wei, Michel, Jennifer Carlisle, Goehring, April, Du, Juan, Song, Xianqiang, Gouaux, Eric |
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Format: | Online |
Language: | English |
Published: |
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263351/ |
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