NMDA receptor structures reveal subunit arrangement and pore architecture
N-methyl-d-aspartate (NMDA) receptors are Hebbian-like coincidence detectors, requiring binding of glycine and glutamate in combination with the relief of voltage-dependent magnesium block to open an ion conductive pore across the membrane bilayer. Despite the importance of the NMDA receptor in the...
Main Authors: | , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
2014
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263351/ |