Piezos are pore-forming subunits of mechanically activated channels

Mechanotransduction plays a crucial role in physiology. Biological processes including sensing touch and sound waves require yet unidentified cation channels that detect pressure. Mouse piezo1 (mpiezo1) and mpiezo2 induce mechanically activated cationic currents in cells; however, it is unknown if p...

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Bibliographic Details
Main Authors: Coste, Bertrand, Xiao, Bailong, Santos, Jose S., Syeda, Ruhma, Grandl, Jörg, Spencer, Kathryn S., Kim, Sung Eun, Schmidt, Manuela, Mathur, Jayanti, Dubin, Adrienne E., Montal, Mauricio, Patapoutian, Ardem
Format: Online
Language:English
Published: 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297710/