Systematic Characterization and Comparative Analysis of the Rabbit Immunoglobulin Repertoire
Rabbits have been used extensively as a model system for the elucidation of the mechanism of immunoglobulin diversification and for the production of antibodies. We employed Next Generation Sequencing to analyze Ig germline V and J gene usage, CDR3 length and amino acid composition, and gene convers...
Main Authors: | Lavinder, Jason J., Hoi, Kam Hon, Reddy, Sai T., Wine, Yariv, Georgiou, George |
---|---|
Format: | Online |
Language: | English |
Published: |
Public Library of Science
2014
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076286/ |
Similar Items
-
Proteomic Identification of Monoclonal Antibodies from Serum
by: Boutz, Daniel R., et al.
Published: (2014) -
Characterizing Immunoglobulin Repertoire from Whole Blood by a Personal Genome Sequencer
by: Gao, Fan, et al.
Published: (2013) -
Differences in the Composition of the Human Antibody Repertoire by B Cell Subsets in the Blood
by: Mroczek, Eva Szymanska, et al.
Published: (2014) -
sciReptor: analysis of single-cell level immunoglobulin repertoires
by: Imkeller, Katharina, et al.
Published: (2016) -
Antibody Repertoires in Humanized NOD-scid-IL2Rγnull Mice and Human B Cells Reveals Human-Like Diversification and Tolerance Checkpoints in the Mouse
by: Ippolito, Gregory C., et al.
Published: (2012)