Systematic Characterization and Comparative Analysis of the Rabbit Immunoglobulin Repertoire

Rabbits have been used extensively as a model system for the elucidation of the mechanism of immunoglobulin diversification and for the production of antibodies. We employed Next Generation Sequencing to analyze Ig germline V and J gene usage, CDR3 length and amino acid composition, and gene convers...

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Bibliographic Details
Main Authors: Lavinder, Jason J., Hoi, Kam Hon, Reddy, Sai T., Wine, Yariv, Georgiou, George
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076286/