Diversity in the pre-immune immunoglobulin repertoire of SHR lines susceptible and resistant to end organ injury
We used next-generation sequencing to identify IGH genetic variation in two closely related hypertensive rat lines that differ in susceptibility to end-organ disease (SHR-A3 and SHR-B2). The two SHR lines differ extensively at the IGH locus from the rat reference genome sequence (RRGS) and from each...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257902/ |