B cell repertoire diversification precedes immunoglobulin receptor expression

68 monoclonal antibodies specific for the hemagglutinin (HA) of the influenza virus, PR8, were obtained from sIg- bone marrow B cell precursors stimulated in splenic fragment cultures. Reactivity pattern (RP) analysis demonstrated that these anti-HA antibody responses included at least 29 distinguis...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1983
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187120/