In vitro genotoxicity testing strategy for nanomaterials and the adaptation of current OECD guidelines

In vitro genotoxicity testing strategy for nanomaterials and the adaptation of current OECD guidelines

► We consider current in vitro OECD genotoxicity tests for nanomaterials. ► Ames test does not appear to be suitable for nanomaterial assessment. ► In vitro HPRT and micronucleus assays require nanomaterial specific protocols. ► We recommend a strategic in vitro genotoxicity testing strategy for nan...

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Bibliographic Details
Main Authors: Doak, S.H., Manshian, B., Jenkins, G.J.S., Singh, N.
Format: Online
Language:English
Published: Elsevier 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028084/

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