In vitro genotoxicity testing strategy for nanomaterials and the adaptation of current OECD guidelines
► We consider current in vitro OECD genotoxicity tests for nanomaterials. ► Ames test does not appear to be suitable for nanomaterial assessment. ► In vitro HPRT and micronucleus assays require nanomaterial specific protocols. ► We recommend a strategic in vitro genotoxicity testing strategy for nan...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Elsevier
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028084/ |